Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 3/20 | 0.51 |
| ▸ | TRHR | P34981 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278685 | 1.00 | OPRM1 (0.53) | OPRM1ACETRHRACE2 | |
| SCHEMBL7271234 | 0.89 | OPRM1 (0.54) | OPRM1ACETRHRACE2 | |
| SCHEMBL7280062 | 0.86 | OPRM1 (0.53) | OPRM1ACETRHRACE2 | |
| SCHEMBL7280071 | 0.86 | OPRM1 (0.53) | OPRM1ACETRHRACE2 | |
| SCHEMBL7273785 | 0.81 | TRHR (0.56) | OPRM1ACETRHR | |
| SCHEMBL7278696 | 0.81 | OPRM1 (0.55) | OPRM1ACETRHR | |
| SCHEMBL7278687 | 0.81 | OPRM1 (0.55) | OPRM1ACETRHR | |
| SCHEMBL7271566 | 0.80 | OPRM1 (0.53) | OPRM1ACETRHRACE2 | |
| SCHEMBL7273818 | 0.79 | TRHR (0.56) | OPRM1ACETRHR | |
| SCHEMBL8072498 | 0.79 | ACE (0.57) | OPRM1ACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0473993-B1 | Novel peptide derivatives and their pharmaceutical use | JAPAN TOBACCO INC (JP) | 1996-04-17 | — | — | EP | disclosed |
| EP-0473993-A2 | Novel peptide derivatives and their pharmaceutical use | Japan Tobacco Inc. (JP) | 1992-03-11 | — | — | EP | disclosed |