Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 6/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.40 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278916 | 1.00 | RAB9A (0.42) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL7379132 | 0.88 | RAB9A (0.40) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL8141861 | 0.87 | EPHX1 (0.44) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL7812490 | 0.85 | SIRT2 (0.44) | RAB9ANPC1SMN1; SMN2EPHX1ACHE | |
| SCHEMBL2455888 | 0.85 | PLA2G2A (0.55) | PLA2G2APLA2G5ALDH1A1FOLH1MAPT | |
| SCHEMBL10703068 | 0.85 | TAS1R3 (0.44) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL6824840 | 0.85 | PLA2G2A (0.55) | PLA2G2APLA2G5ALDH1A1FOLH1MAPT | |
| SCHEMBL1068731 | 0.85 | PLA2G2A (0.55) | PLA2G2APLA2G5ALDH1A1FOLH1MAPT | |
| SCHEMBL7769892 | 0.85 | PPID (0.42) | ALDH1A1TAS1R3TAS1R1CA12CA1 | |
| SCHEMBL7819315 | 0.84 | NPC1 (0.42) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |