Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.49 |
| ▸ | ECE1 | P42892 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285371 | 0.85 | MME (0.46) | MMEECE1CTSLCTSSSIRT2 | |
| SCHEMBL7285383 | 0.85 | MME (0.46) | MMEECE1CTSLCTSSSIRT2 | |
| SCHEMBL7278952 | 0.78 | CTSL (0.49) | MMEECE1CTSLCTSSSIRT2 | |
| SCHEMBL11332452 | 0.76 | CTSL (0.72) | MMEECE1CTSLCTSSSIRT2 | |
| SCHEMBL4126228 | 0.76 | CTSL (0.72) | MMEECE1CTSLCTSSSIRT2 | |
| SCHEMBL150166 | 0.76 | CTSL (0.72) | MMEECE1CTSLCTSSSIRT2 | |
| Hydrochloric Acid SCHEMBL4438043 | 0.75 | CTSL (0.70) | MMEECE1CTSLCTSSSIRT2 | |
| SCHEMBL7279460 | 0.75 | CTSL (0.46) | MMEECE1CTSLCTSSSIRT2 | |
| SCHEMBL8744667 | 0.74 | CTSK (0.68) | MMEECE1CTSLCTSSCTSK | |
| SCHEMBL8744665 | 0.74 | CTSK (0.68) | MMEECE1CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272583-B1 | 5-SUBSTITUTED AMINO-4-HYDROXY-PENTENOIC ACID DERIVATIVES AND THEIR USE | Banyu Pharmaceutical Co., Ltd. (JP) | 1993-09-15 | — | — | EP | disclosed |
| US-4927565-A | HYPOTENSIVE AGENT | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1990-05-22 | — | — | US | disclosed |
| EP-0272583-A2 | 5-Substituted amino-4-hydroxy-pentenoic acid derivatives and their use | Banyu Pharmaceutical Co., Ltd. (JP) | 1988-06-29 | — | — | EP | disclosed |