Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 3/20 | 0.59 |
| ▸ | CPB1 | P15086 | 1/20 | 0.59 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.59 |
| ▸ | CTSK | P43235 | 2/20 | 0.55 |
| ▸ | MME | P08473 | 2/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.53 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | PLG | P00747 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29576990 | 0.97 | ECE1 (0.63) | ECE1CPB1CPB2CTSKMME | |
| SCHEMBL10035700 | 0.93 | CTSK (0.55) | ECE1CPB1CPB2CTSKITGB3 | |
| SCHEMBL10035721 | 0.93 | CTSK (0.55) | ECE1CPB1CPB2CTSKITGB3 | |
| SCHEMBL24188458 | 0.89 | ECE1 (0.62) | ECE1CPB1CPB2MMEITGB3 | |
| SCHEMBL210602 | 0.89 | ITGB3 (0.64) | ECE1CPB1CPB2ITGB3ITGA2B | |
| SCHEMBL210601 | 0.89 | ITGB3 (0.64) | ECE1CPB1CPB2ITGB3ITGA2B | |
| SCHEMBL2367228 | 0.89 | ITGB3 (0.64) | ECE1CPB1CPB2ITGB3ITGA2B | |
| SCHEMBL7279464 | 0.88 | CTSK (0.55) | ECE1CPB1CPB2CTSKMME | |
| Hydrochloric Acid SCHEMBL2500832 | 0.88 | ITGB3 (0.63) | ECE1CPB1CPB2ITGB3ITGA2B | |
| SCHEMBL10067246 | 0.87 | CTSL (0.53) | ECE1CPB1CPB2CTSKMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112175042-B | Method for synthesizing Etelcalcetide | 深圳翰宇药业股份有限公司 | 2022-05-31 | — | — | CN | disclosed |