Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | HMGCR | P04035 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273563 | 0.90 | ALOX5 (0.47) | AOC3KDM4EALDH1A1ALOX5SMN1; SMN2 | |
| SCHEMBL7274253 | 0.86 | SLC2A1 (0.45) | AOC3KDM4EALDH1A1PDE4APDE4B | |
| SCHEMBL11300908 | 0.85 | AOC3 (0.46) | AOC3KDM4EALDH1A1PDE4APDE4B | |
| SCHEMBL30056339 | 0.85 | AOC3 (0.46) | AOC3KDM4EALDH1A1PDE4APDE4B | |
| SCHEMBL1340134 | 0.81 | AOC3 (0.53) | AOC3KDM4EALDH1A1PDE4APDE4B | |
| SCHEMBL7273729 | 0.81 | SLC2A1 (0.52) | AOC3KDM4EALDH1A1SMN1; SMN2POLB | |
| SCHEMBL7432783 | 0.81 | KDM4E (0.52) | AOC3KDM4EALDH1A1SMN1; SMN2POLB | |
| SCHEMBL7442211 | 0.81 | TUBB4A (0.55) | AOC3PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL7273721 | 0.80 | TAAR1 (0.46) | AOC3KDM4ECYP1A2TAAR1SLC2A1 | |
| SCHEMBL7272748 | 0.80 | KDM4E (0.57) | AOC3KDM4EALDH1A1PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4885313-A | 3,4-Dihydroxyphenylethylamine derivatives and their use | FISONS PLC (GB) | 1989-12-05 | — | — | US | disclosed |
| US-4803225-A | Dihydroxy-phenethylamino compounds useful as pharmaceuticals | FISONS, PLC (GB) | 1989-02-07 | — | — | US | disclosed |
| US-4720586-A | Substituted 3,4-dihydroxy-phenylethylamino compounds | FISONS, PLC (GB) | 1988-01-19 | — | — | US | disclosed |
| EP-0142283-A2 | Phenylethylamines, process for their preparation and compositions containing them | FISONS plc (GB) | 1985-05-22 | — | — | EP | disclosed |