SCHEMBL728383

SCHEMBL728383

CCCCC(CCC)OC(=O)C(CC(=O)O)N(CCC)[Si](OC)(OC)OC

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CTSK P43235 2/20 0.33
GPR84 Q9NQS5 4/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL729848 0.93 CTSK (0.31) CTSK
SCHEMBL730367 0.89 CTSK (0.33) CTSKGPR84
SCHEMBL728025 0.79 LMNA (0.30)
SCHEMBL729831 0.73 CTSK (0.30) CTSK
SCHEMBL1242013 0.71 GPR84 (0.43) CTSKGPR84CA1CA2CYP1A2
SCHEMBL729754 0.69 CTSK (0.36) CTSKGPR84CA1CA2CYP1A2
SCHEMBL9834524 0.68 GPR84 (0.51) GPR84CYP1A2
SCHEMBL3425435 0.68 RECQL (0.46) CTSKGPR84CA1CA2CYP1A2
SCHEMBL730337 0.68 LMNA (0.30)
SCHEMBL9833428 0.68 GPR84 (0.51) GPR84CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP claimed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US claimed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US claimed
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP disclosed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US disclosed
EP-2393861-A1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY Momentive Performance Materials Inc. (US) 2011-12-14 EP disclosed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US disclosed
WO-2010091338-A1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-08-12 WO disclosed