Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 12/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.40 |
| ▸ | F2 | P00734 | 3/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | ITGAV | P06756 | 2/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7274763 | 0.92 | OPRM1 (0.40) | F10ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL7273436 | 0.88 | ALDH1A1 (0.36) | F10F2PRSS1OPRM1OPRD1 | |
| SCHEMBL7283239 | 0.88 | DRD2 (0.39) | F10F2PRSS1OPRM1OPRD1 | |
| SCHEMBL7276057 | 0.85 | ITGB3 (0.42) | ITGB3ITGA2BF2ITGAV | |
| SCHEMBL7275515 | 0.85 | ALDH1A1 (0.38) | OPRM1OPRD1PTGER4OPRK1KCNH2 | |
| SCHEMBL7283562 | 0.84 | ALDH1A1 (0.38) | ITGB3ITGA2BOPRM1OPRD1PTGER4 | |
| SCHEMBL7276485 | 0.84 | ITGB3 (0.41) | ITGB3ITGA2BF2ITGAV | |
| SCHEMBL7284030 | 0.83 | ALDH1A1 (0.39) | ITGB3ITGA2BOPRM1OPRD1PTGER4 | |
| SCHEMBL7284946 | 0.82 | F10 (0.48) | F10ITGB3ITGA2BPRSS1ITGAV | |
| SCHEMBL7275019 | 0.81 | ITGB3 (0.40) | ITGB3ITGA2BF2OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |