Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273436 | 0.94 | ALDH1A1 (0.36) | DRD2DRD4PTGER4ALDH1A1TSHR | |
| SCHEMBL7275591 | 0.91 | DRD2 (0.38) | DRD2DRD4PTGER4CHRNB2CHRNB4 | |
| SCHEMBL7284940 | 0.88 | F10 (0.41) | PTGER4OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL7284030 | 0.87 | ALDH1A1 (0.39) | PTGER4ALDH1A1TSHRSMN1; SMN2SIGMAR1 | |
| SCHEMBL7275707 | 0.85 | OPRM1 (0.35) | OPRM1OPRD1OPRK1KCNH2F2 | |
| SCHEMBL7282388 | 0.85 | ALDH1A1 (0.39) | PTGER4ALDH1A1TSHRSMN1; SMN2SIGMAR1 | |
| SCHEMBL7272761 | 0.83 | SIGMAR1 (0.43) | PTGER4ALDH1A1TSHRSMN1; SMN2SIGMAR1 | |
| SCHEMBL7275515 | 0.83 | ALDH1A1 (0.38) | PTGER4ALDH1A1TSHRSMN1; SMN2SIGMAR1 | |
| SCHEMBL7283562 | 0.82 | ALDH1A1 (0.38) | PTGER4ALDH1A1TSHRSMN1; SMN2SIGMAR1 | |
| SCHEMBL7274763 | 0.82 | OPRM1 (0.40) | ALDH1A1TSHRSMN1; SMN2OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |