Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 3/20 | 0.38 |
| ▸ | PTPRC | P08575 | 2/20 | 0.38 |
| ▸ | S100A4 | P26447 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29412464 | 1.00 | CYP2A6 (0.48) | CYP2A6MAOAMAOBKMT2ATDP2 | |
| SCHEMBL2171651 | 0.96 | CYP2A6 (0.44) | CYP2A6MAOAMAOBKMT2ATDP2 | |
| SCHEMBL8118609 | 0.89 | MAOA (0.46) | CYP2A6MAOAMAOBKMT2ATDP2 | |
| SCHEMBL29439737 | 0.88 | TDP2 (0.45) | KMT2ATDP2NSD2ABL1PLCG1 | |
| SCHEMBL2456241 | 0.88 | TDP2 (0.45) | KMT2ATDP2NSD2ABL1PLCG1 | |
| SCHEMBL4912110 | 0.85 | TSHR (0.43) | CYP2A6MAOAMAOBKMT2ATDP2 | |
| SCHEMBL829095 | 0.80 | TDP2 (0.52) | CYP2A6MAOAMAOBKMT2ATDP2 | |
| SCHEMBL13813397 | 0.76 | HRH1 (0.37) | CYP2A6MAOAMAOBKMT2ATDP2 | |
| SCHEMBL13857918 | 0.76 | HRH1 (0.37) | CYP2A6MAOAMAOBKMT2ATDP2 | |
| SCHEMBL4069326 | 0.76 | HRH1 (0.37) | CYP2A6MAOAMAOBKMT2ATDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 530 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025107466-A1 | METHOD FOR PREPARING CHIRAL CYCLIC AMINE BY ASYMMETRIC HYDROGENATION, CATALYST USED THEREIN, AND CATALYST PREPARATION METHOD | 河北师范大学 | 2025-05-30 | — | — | WO | claimed |
| CN-117567523-A | Method for preparing chiral cyclic amine by asymmetric hydrogenation, catalyst used by method and catalyst preparation method | 河北师范大学 | 2024-02-20 | — | — | CN | claimed |
| CN-116925154-A | Dibenzocycloheptyl group-containing pyrido ring metal complex and application thereof in olefin polymerization | 北京服装学院 | 2023-10-24 | — | — | CN | claimed |
| CN-110698513-B | Preparation of trihydroquinoline amine metal compound and application of trihydroquinoline amine metal compound in high-temperature solution polymerization of olefin | 青岛科技大学 | 2022-06-17 | — | — | CN | claimed |
| CN-112409357-B | Novel functional nitrogen heterocyclic compound and preparation method and application thereof | 广东省测试分析研究所（中国广州分析测试中心） | 2022-01-18 | — | — | CN | claimed |
| CN-112409357-A | Novel functional nitrogen heterocyclic compound and preparation method and application thereof | 广东省测试分析研究所（中国广州分析测试中心） | 2021-02-26 | — | — | CN | claimed |
| CN-110698513-A | Preparation of trihydroquinoline amine metal compound and application of trihydroquinoline amine metal compound in high-temperature solution polymerization of olefin | 青岛科技大学 | 2020-01-17 | — | — | CN | claimed |
| CN-103833561-B | The N-arylation method of alkane amine | HENGYANG NORMAL UNIVERSITY (CN) | 2016-01-13 | — | — | CN | claimed |
| CN-103833561-A | Method for N-arylation of alkane amine | UNIV HENGYANG NORMAL | 2014-06-04 | — | — | CN | claimed |
| US-12617789-B2 | Small molecular inhibitors of NF-κb inducing kinase | JANSSEN PHARMACEUTICA NV (BE) | 2026-05-05 | — | — | US | disclosed |
| US-12583858-B2 | TDO2 inhibitors | GENENTECH, INC. (US) | 2026-03-24 | — | — | US | disclosed |
| US-20260022132-A1 | SPIROCYCLIC DIHYDROPYRANOPYRIMIDINE KRAS INHIBITORS | TREELINE BIOSCIENCES INC (US) | 2026-01-22 | — | — | US | disclosed |
| EP-4163277-B1 | NOVEL PYRAZOLE DERIVATIVES | APTABIO THERAPEUTICS INC (KR) | 2026-01-14 | — | — | EP | disclosed |
| US-20250388601-A1 | Compounds, Compositions and Methods | DENALI THERAPEUTICS INC. (US) | 2025-12-25 | — | — | US | disclosed |
| WO-1997045428-A1 | NOVEL PYRIDAZINE COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-12-04 | — | — | WO | disclosed |
| US-5606054-A | Heterocyclic-fused lactams promote release of growth hormone | MERCK & CO., INC. (US) | 1997-02-25 | — | — | US | disclosed |
| CN-1143364-A | 5-HT3 receptor agonist, novel thiazole derivative, and intermediate thereof | YAMANOUCHI PHARMA CO LTD (JP) | 1997-02-19 | — | — | CN | disclosed |
| EP-0749966-A1 | 5-HT 3 RECEPTOR AGONIST, NOVEL THIAZOLE DERIVATIVE, AND INTERMEDIATE THEREFOR | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-12-27 | — | — | EP | disclosed |
| WO-1995016692-A1 | HETEROCYCLIC-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-06-22 | — | — | WO | disclosed |
| US-5304554-A | Intercalators of DNA, inhibit replication of retroviruses | EMORY UNIVERSITY (US) | 1994-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12583858-B2 | TDO2 inhibitors | TDO2, IDO2, TPH2 | CYP2A6 136/4885MAOA 18/4885MAOB 26/4885 |
| US-20260022132-A1 | SPIROCYCLIC DIHYDROPYRANOPYRIMIDINE KRAS INHIBITORS | KRAS, NRAS, G3BP2 | CYP2A6 320/4885MAOA 4501/4885MAOB 3147/4885 |
| US-20250388601-A1 | Compounds, Compositions and Methods | AURKC, WEE2, ERBB2 | CYP2A6 245/4885MAOA 2277/4885MAOB 1268/4885 |
| US-12617789-B2 | Small molecular inhibitors of NF-κb inducing kinase | IRAK3, IKBKB, IKBKG | CYP2A6 4230/4885MAOA 4530/4885MAOB 4372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.