Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285612 | 0.84 | HKDC1 (0.31) | — | |
| SCHEMBL6671659 | 0.77 | NR1H4 (0.42) | CA2CA4CA5A | |
| SCHEMBL507894 | 0.74 | CYP1A2 (0.33) | — | |
| SCHEMBL7900149 | 0.74 | — | — | |
| SCHEMBL7277057 | 0.74 | — | — | |
| SCHEMBL9030835 | 0.73 | CA2 (0.37) | CA2CA4CA5A | |
| SCHEMBL5973107 | 0.73 | CA1 (0.44) | CA2 | |
| SCHEMBL17111856 | 0.72 | RXRA (0.41) | CA2 | |
| SCHEMBL2529899 | 0.70 | CYP3A4 (0.36) | — | |
| SCHEMBL8348640 | 0.70 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509769-B1 | Heterocyclic amides having HLE inhibiting activity | ZENECA LTD (GB) | 1996-09-11 | — | — | EP | disclosed |
| US-5521179-A | Heterocyclic amides | ZENECA LIMITED (GB) | 1996-05-28 | — | — | US | disclosed |
| EP-0509769-A2 | Heterocyclic amides having HLE inhibiting activity | ZENECA LIMITED (GB) | 1992-10-21 | — | — | EP | disclosed |