Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP12 | P39900 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7296041 | 0.99 | PKM (0.46) | PKMTAAR1TSHRSMN1; SMN2MMP1 | |
| SCHEMBL7286003 | 0.69 | PKM (0.40) | PKMTAAR1TSHRSMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL7295298 | 0.68 | PKM (0.39) | PKMTAAR1TSHRSMN1; SMN2HTT | |
| SCHEMBL29410307 | 0.64 | ALDH1A1 (0.52) | PKMTAAR1TSHRSMN1; SMN2GAA | |
| SCHEMBL14703128 | 0.62 | GRIN1 (0.49) | TAAR1TSHRSMN1; SMN2ALDH1A1GRIN1 | |
| SCHEMBL28775033 | 0.62 | GRIN1 (0.61) | PKMTAAR1TSHRSMN1; SMN2GAA | |
| SCHEMBL21966469 | 0.62 | ALDH1A1 (0.53) | PKMTAAR1TSHRSMN1; SMN2HTT | |
| SCHEMBL3103042 | 0.60 | GRIN1 (0.50) | PKMTAAR1TSHRSMN1; SMN2GAA | |
| SCHEMBL8990090 | 0.60 | ALDH1A1 (0.47) | PKMTAAR1TSHRSMN1; SMN2GAA | |
| SCHEMBL8393618 | 0.60 | ALDH1A1 (0.61) | TAAR1TSHRSMN1; SMN2GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239533-B1 | PYRIDINE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-09-16 | — | — | EP | claimed |