Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7295298 | 0.99 | PKM (0.39) | PKMHTTTAAR1GRIN1GRIN2B | |
| SCHEMBL7285267 | 0.69 | PKM (0.47) | PKMHTTTAAR1GRIN1GRIN2B | |
| Hydrochloric Acid SCHEMBL7296041 | 0.68 | PKM (0.46) | PKMHTTTAAR1GRIN1GRIN2B | |
| SCHEMBL23121611 | 0.66 | TSPO (0.50) | HTTTSHRSMN1; SMN2LMNAMAPT | |
| SCHEMBL11672382 | 0.66 | KCNH2 (0.73) | SMN1; SMN2TDP1ALDH1A1KCNH2KDM4E | |
| SCHEMBL11621298 | 0.65 | NCF1 (0.43) | PKMTSHRSMN1; SMN2HIF1ACYP2D6 | |
| SCHEMBL14703128 | 0.63 | GRIN1 (0.49) | TAAR1GRIN1GRIN2BTSHRSMN1; SMN2 | |
| SCHEMBL21966469 | 0.62 | ALDH1A1 (0.53) | PKMHTTTAAR1GRIN1GRIN2B | |
| SCHEMBL25226261 | 0.62 | CNR1 (0.41) | ADRA2AADRA2BALDH1A1 | |
| SCHEMBL28775033 | 0.62 | GRIN1 (0.61) | PKMHTTTAAR1GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239533-B1 | PYRIDINE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-09-16 | — | — | EP | claimed |
| US-4863938-A | Pyridine derivatives and their use as nootropic agents | CIBA-GEIGY CORPORATION (US) | 1989-09-05 | — | — | US | claimed |