SCHEMBL728589

SCHEMBL728589

CCOC(=O)C(CC(=O)O)NC[Si](OC)(OCC)OCC

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.32
CAD P27708 1/20 0.32
POLB P06746 2/20 0.31
KMT2A Q03164 2/20 0.31
APEX1 P27695 1/20 0.30
CTDSP1 Q9GZU7 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL730350 0.92 L3MBTL1 (0.34) L3MBTL1CADPOLBKMT2AAPEX1
SCHEMBL730224 0.92 L3MBTL1 (0.37) L3MBTL1CADPOLBKMT2AAPEX1
SCHEMBL728669 0.88 L3MBTL1 (0.38) L3MBTL1CADPOLBKMT2ATDP1
SCHEMBL728606 0.87 L3MBTL1 (0.39) L3MBTL1CADPOLBKMT2ATDP1
SCHEMBL728670 0.85 MAPT (0.33)
SCHEMBL728588 0.81 MAPT (0.32)
SCHEMBL728426 0.80 CTSK (0.34)
SCHEMBL728627 0.80 L3MBTL1 (0.44) L3MBTL1CADPOLBKMT2ATDP1
SCHEMBL730300 0.80 L3MBTL1 (0.41) L3MBTL1CADPOLBKMT2ATDP1
SCHEMBL17505034 0.78 SMN1; SMN2 (0.35) L3MBTL1CADPOLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP claimed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US claimed
EP-2393861-A1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY Momentive Performance Materials Inc. (US) 2011-12-14 EP claimed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US claimed
WO-2010091338-A1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-08-12 WO claimed
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP disclosed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US disclosed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US disclosed