SCHEMBL730300

SCHEMBL730300

CCOC(=O)CC(NC[Si](OCC)(OCC)OCC)C(=O)OCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
KMT2A Q03164 2/20 0.39
POLB P06746 1/20 0.39
ALDH1A1 P00352 5/20 0.36
TSHR P16473 3/20 0.36
CYP3A4 P08684 2/20 0.36
ALOX15 P16050 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
HSD17B10 Q99714 2/20 0.35
CHRM1 P11229 1/20 0.35
ADORA1 P30542 1/20 0.35
CAD P27708 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL728606 0.94 L3MBTL1 (0.39) L3MBTL1MGAMGAASIMGAM2
SCHEMBL728669 0.92 L3MBTL1 (0.38) L3MBTL1MGAMGAASIMGAM2
SCHEMBL730350 0.87 L3MBTL1 (0.34) L3MBTL1MGAMGAASIMGAM2
SCHEMBL728627 0.87 L3MBTL1 (0.44) L3MBTL1MGAMGAASIMGAM2
SCHEMBL730349 0.84 CA12 (0.32) MGAMGAASIMGAM2MAPT
SCHEMBL729761 0.84 ALDH1A1 (0.37) L3MBTL1POLBALDH1A1TSHRHSD17B10
SCHEMBL1931813 0.82 KMT2A (0.38) L3MBTL1MGAMGAASIMGAM2
SCHEMBL1931815 0.82 KMT2A (0.38) L3MBTL1MGAMGAASIMGAM2
SCHEMBL730268 0.81 CA12 (0.30)
SCHEMBL728589 0.80 L3MBTL1 (0.32) L3MBTL1KMT2APOLBTDP1CAD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP claimed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US claimed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US claimed
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP disclosed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US disclosed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US disclosed