SCHEMBL730224

SCHEMBL730224

CCOC(=O)C(CC(=O)O)NC[Si](OC)(OC)OC

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.37
KMT2A Q03164 3/20 0.36
POLB P06746 2/20 0.36
CAD P27708 1/20 0.34
PIN1 Q13526 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
APEX1 P27695 1/20 0.32
CTDSP1 Q9GZU7 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
P2RY12 Q9H244 2/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP2D6 P10635 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL728589 0.92 L3MBTL1 (0.32) L3MBTL1KMT2APOLBCADAPEX1
SCHEMBL730350 0.87 L3MBTL1 (0.34) L3MBTL1KMT2APOLBCADPIN1
SCHEMBL728627 0.87 L3MBTL1 (0.44) L3MBTL1KMT2APOLBCADTDP1
SCHEMBL3714483 0.83 CA2 (0.36) TDP1SMN1; SMN2
SCHEMBL23795575 0.82 SMN1; SMN2 (0.35) L3MBTL1KMT2APOLBCADEGLN1
SCHEMBL728628 0.82 MAPT (0.35)
SCHEMBL728606 0.81 L3MBTL1 (0.39) L3MBTL1KMT2APOLBCADTDP1
SCHEMBL728669 0.80 L3MBTL1 (0.38) L3MBTL1KMT2APOLBCADTDP1
SCHEMBL728670 0.78 MAPT (0.33)
SCHEMBL729754 0.77 CTSK (0.36) KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP claimed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US claimed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US claimed
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP disclosed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US disclosed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US disclosed