Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | TFEB | P19484 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.47 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4827936 | 1.00 | NFE2L2 (0.56) | NFE2L2TRPA1TFEBKDM4EALDH1A1 | |
| SCHEMBL30678623 | 0.86 | NFE2L2 (0.62) | NFE2L2TRPA1TFEBKDM4EALDH1A1 | |
| SCHEMBL29805387 | 0.86 | NFE2L2 (0.62) | NFE2L2TRPA1TFEBKDM4EALDH1A1 | |
| SCHEMBL7286837 | 0.84 | NFE2L2 (0.58) | NFE2L2KDM4ECYP1A2CYP1A1CYP1B1 | |
| SCHEMBL8609021 | 0.84 | NFE2L2 (0.58) | NFE2L2KDM4ECYP1A2CYP1A1CYP1B1 | |
| SCHEMBL257125 | 0.82 | NFE2L2 (0.58) | NFE2L2TRPA1TFEBKDM4EALDH1A1 | |
| SCHEMBL29372144 | 0.82 | NFE2L2 (0.58) | NFE2L2TRPA1TFEBKDM4EALDH1A1 | |
| SCHEMBL5085210 | 0.82 | NFE2L2 (0.58) | NFE2L2TRPA1TFEBKDM4EALDH1A1 | |
| SCHEMBL11585177 | 0.81 | MAPT (0.51) | KDM4EALDH1A1CYP1A2SMN1; SMN2NPC1 | |
| SCHEMBL11585180 | 0.81 | MAPT (0.51) | KDM4EALDH1A1CYP1A2SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3527593-B1 | ISOCYANATE COMPOSITION, METHOD FOR PRODUCING ISOCYANATE COMPOSITION, AND METHOD FOR PRODUCING ISOCYANATE POLYMER | ASAHI CHEMICAL IND (JP) | 2025-07-23 | — | — | EP | disclosed |
| EP-3527600-B1 | ISOCYANATE COMPOSITION AND PRODUCTION METHOD FOR ISOCYANATE POLYMER | ASAHI CHEMICAL IND (JP) | 2025-07-09 | — | — | EP | disclosed |
| CN-112979917-B | Isocyanate composition, method for producing isocyanate composition, and method for producing isocyanate polymer | 旭化成株式会社 | 2023-04-25 | — | — | CN | disclosed |
| US-20230114799-A1 | ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2023-04-13 | — | — | US | disclosed |
| US-11548975-B2 | Isocyanate composition and method for producing isocyanate polymer | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2023-01-10 | — | — | US | disclosed |
| EP-3536683-B1 | POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION | ASAHI CHEMICAL IND (JP) | 2021-11-24 | — | — | EP | disclosed |
| US-11118001-B2 | Isocyanate composition, method for producing isocyanate composition, and method for producing isocyanate polymer | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2021-09-14 | — | — | US | disclosed |
| US-11078321-B2 | — | — | 2021-08-03 | — | — | US | disclosed |
| US-20200048403-A1 | ISOCYANATE COMPOSITION, METHOD FOR PRODUCING ISOCYANATE COMPOSITION, AND METHOD FOR PRODUCING ISOCYANATE POLYMER | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2020-02-13 | — | — | US | disclosed |
| EP-3536683-A1 | POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION | Asahi Kasei Kabushiki Kaisha (JP) | 2019-09-11 | — | — | EP | disclosed |
| US-10125212-B2 | Polyisocyanate composition and isocyanate polymer composition | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2018-11-13 | — | — | US | disclosed |
| EP-3372579-A1 | POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION | Asahi Kasei Kabushiki Kaisha (JP) | 2018-09-12 | — | — | EP | disclosed |
| US-20170298169-A1 | Polyisocyanate Composition and Isocyanate Polymer Composition | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2017-10-19 | — | — | US | disclosed |
| EP-2915803-A1 | POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION | Asahi Kasei Chemicals Corporation (JP) | 2015-09-09 | — | — | EP | disclosed |
| US-20150210631-A1 | Polyisocyanate Composition and Isocyanate Polymer Composition | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2015-07-30 | — | — | US | disclosed |
| US-5942387-A | Combinatorial process for preparing substituted thiophene libraries | ELI LILLY AND COMPANY (US) | 1999-08-24 | — | — | US | disclosed |
| EP-0825164-A2 | Scavenger assisted combinatorial process for preparing libraries of amides, carbamates and sulfonamides | ELI LILLY AND COMPANY (US) | 1998-02-25 | — | — | EP | disclosed |
| EP-0347766-B1 | 4,5,7,8-Tetrahydro-6H-thiazolo[5,4-d]azepines, their preparation and their use as medicaments | THOMAE GMBH DR K (DE) | 1994-05-25 | — | — | EP | disclosed |
| US-5068325-A | Dopaminergic systems as hypotensives, sedatives, antitussives and/or antiphlogistics | KARL THOMAE GMBH (DE) | 1991-11-26 | — | — | US | disclosed |
| EP-0347766-A2 | 4,5,7,8-Tetrahydro-6H-thiazolo[5,4-d]azepines, their preparation and their use as medicaments | Dr. Karl Thomae GmbH (DE) | 1989-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11548975-B2 | Isocyanate composition and method for producing isocyanate polymer | IDH3A, IDH2, IDH3B | NFE2L2 1131/4885TRPA1 899/4885TFEB 4785/4885 |
| US-11078321-B2 | — | IDH3A, IPO4, F12 | NFE2L2 3721/4885TRPA1 915/4885TFEB 4832/4885 |
| US-20170298169-A1 | Polyisocyanate Composition and Isocyanate Polymer Composition | TST, SUDS3, SCLY | NFE2L2 382/4885TRPA1 189/4885TFEB 4416/4885 |
| US-20230114799-A1 | ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER | IDH3A, IDH2, IDH3B | NFE2L2 1150/4885TRPA1 953/4885TFEB 4757/4885 |
| US-10125212-B2 | Polyisocyanate composition and isocyanate polymer composition | TST, SUDS3, SCLY | NFE2L2 382/4885TRPA1 189/4885TFEB 4416/4885 |
| US-11118001-B2 | Isocyanate composition, method for producing isocyanate composition, and method for producing isocyanate polymer | IDH3A, IPO4, IDH3B | NFE2L2 4262/4885TRPA1 1596/4885TFEB 4869/4885 |
| US-20150210631-A1 | Polyisocyanate Composition and Isocyanate Polymer Composition | TST, SUDS3, SCLY | NFE2L2 382/4885TRPA1 189/4885TFEB 4416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.