Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276724 | 1.00 | ACE (0.51) | ACEITGB3ITGA2BKDM4EPKM | |
| SCHEMBL7274902 | 0.93 | ACE (0.49) | ACEKDM4EPKMSTSGPR119 | |
| SCHEMBL7274696 | 0.83 | ITGB3 (0.44) | ITGB3ITGA2BKDM4EPKMHPGD | |
| SCHEMBL7277084 | 0.81 | FAAH (0.46) | KDM4EPKMHPGDGPR119FAAH | |
| Acetic Acid SCHEMBL9738719 | 0.77 | KDM4E (0.44) | KDM4EPKMHPGDGPR119FAAH | |
| SCHEMBL7367544 | 0.77 | KDM4E (0.46) | KDM4EPKMGPR119FAAH | |
| SCHEMBL7274867 | 0.76 | KDM4E (0.45) | KDM4EPKMGPR119FAAH | |
| SCHEMBL7286474 | 0.75 | DDB1 (0.46) | KDM4EPKMHPGDGPR119FAAH | |
| SCHEMBL7957340 | 0.75 | KDM4E (0.46) | KDM4EPKMSTSHPGDGPR119 | |
| SCHEMBL8892804 | 0.73 | KDM4E (0.55) | KDM4EPKMHPGDGPR119FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512831-B1 | Fibrinogen receptor antagonists | MERCK & CO INC (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5455243-A | Anticoagulants | MERCK & CO., INC. (US) | 1995-10-03 | — | — | US | disclosed |
| US-5281585-A | Secondary amide containing antagonist | MERCK & CO., INC. (US) | 1994-01-25 | — | — | US | disclosed |
| EP-0512831-A1 | Fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1992-11-11 | — | — | EP | disclosed |