⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7286157 | 0.84 | GRIN2D (0.32) | — | |
| SCHEMBL7287110 | 0.70 | ALDH1A1 (0.37) | — | |
| SCHEMBL7293169 | 0.69 | MMP1 (0.35) | — | |
| SCHEMBL10463822 | 0.66 | ELANE (0.37) | — | |
| SCHEMBL25226261 | 0.63 | CNR1 (0.41) | — | |
| SCHEMBL7286062 | 0.63 | MAPK14 (0.30) | — | |
| SCHEMBL7287783 | 0.62 | CNR2 (0.31) | — | |
| SCHEMBL24485924 | 0.62 | KCNA5 (0.35) | — | |
| SCHEMBL7295809 | 0.62 | MAPK8 (0.37) | — | |
| SCHEMBL10567467 | 0.62 | MAPK8 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4863938-A | Pyridine derivatives and their use as nootropic agents | CIBA-GEIGY CORPORATION (US) | 1989-09-05 | — | — | US | claimed |
| EP-0239533-B1 | PYRIDINE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-09-16 | — | — | EP | disclosed |
| US-4863938-A | Pyridine derivatives and their use as nootropic agents | CIBA-GEIGY CORPORATION (US) | 1989-09-05 | — | — | US | disclosed |