Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MASP2 | O00187 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288253 | 0.78 | ALDH1A1 (0.44) | SMN1; SMN2RAB9AALDH1A1NPC1KDM4E | |
| SCHEMBL2799383 | 0.78 | ALDH1A1 (0.50) | POLBSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL7046389 | 0.77 | ALDH1A1 (0.54) | POLBSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL6883125 | 0.77 | CXCR4 (0.42) | POLBSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL9790100 | 0.76 | ALDH1A1 (0.48) | POLBSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL2802535 | 0.76 | ALDH1A1 (0.48) | POLBSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL7298822 | 0.75 | SMN1; SMN2 (0.40) | POLBSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL9676124 | 0.75 | ATP4A (0.40) | POLBSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL6439248 | 0.75 | CXCR4 (0.41) | POLBSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL9560922 | 0.73 | DDAH1 (0.51) | POLBSMN1; SMN2RAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |