Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.43 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.43 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.40 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATP4A | P20648 | 1/20 | 0.37 |
| ▸ | ATP4B | P51164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7396251 | 0.80 | ALDH1A1 (0.48) | ALDH1A1NPC1RAB9ASMN1; SMN2BCHE | |
| SCHEMBL7072087 | 0.79 | SPHK2 (0.44) | ALDH1A1NPC1RAB9ASMN1; SMN2SPHK2 | |
| SCHEMBL7288146 | 0.78 | POLB (0.45) | ALDH1A1NPC1RAB9ASMN1; SMN2DDAH1 | |
| SCHEMBL9422145 | 0.76 | DDAH1 (0.47) | ALDH1A1NPC1RAB9ASMN1; SMN2BCHE | |
| SCHEMBL31315697 | 0.73 | ALDH1A1 (0.55) | ALDH1A1NPC1RAB9ASMN1; SMN2BCHE | |
| SCHEMBL31315682 | 0.73 | ALDH1A1 (0.55) | ALDH1A1NPC1RAB9ASMN1; SMN2BCHE | |
| SCHEMBL31315691 | 0.73 | ALDH1A1 (0.55) | ALDH1A1NPC1RAB9ASMN1; SMN2BCHE | |
| SCHEMBL7139490 | 0.72 | CXCR4 (0.37) | ALDH1A1NPC1RAB9ASMN1; SMN2BCHE | |
| SCHEMBL2799383 | 0.72 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9ASMN1; SMN2BCHE | |
| SCHEMBL9560922 | 0.71 | DDAH1 (0.51) | ALDH1A1NPC1RAB9ASMN1; SMN2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |