Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MASP2 | O00187 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354306 | 0.89 | EPHX2 (0.47) | EPHX2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL7351165 | 0.88 | EPHX2 (0.46) | EPHX2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL7289169 | 0.87 | RAB9A (0.46) | EPHX2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL7288152 | 0.84 | NPC1 (0.43) | NPC1RAB9AALDH1A1KDM4EABCB11 | |
| SCHEMBL9509188 | 0.81 | RAB9A (0.54) | NPC1RAB9AALDH1A1KDM4EABCB11 | |
| SCHEMBL10867335 | 0.80 | ACHE (0.50) | NPC1RAB9AALDH1A1KDM4EABCB11 | |
| SCHEMBL7289458 | 0.80 | DDAH1 (0.41) | NPC1RAB9AALDH1A1KDM4EABCB11 | |
| SCHEMBL9560922 | 0.80 | DDAH1 (0.51) | NPC1RAB9AALDH1A1KDM4EABCB11 | |
| SCHEMBL7289165 | 0.80 | NPC1 (0.46) | NPC1RAB9AALDH1A1KDM4EABCB11 | |
| SCHEMBL9422145 | 0.79 | DDAH1 (0.47) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |