Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDAH1 | O94760 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.47 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.47 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TXN | P10599 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288257 | 0.86 | DDAH1 (0.41) | DDAH1NPC1RAB9ABCHEALDH1A1 | |
| SCHEMBL7351165 | 0.86 | EPHX2 (0.46) | DDAH1NPC1RAB9ABCHEALDH1A1 | |
| SCHEMBL7354306 | 0.84 | EPHX2 (0.47) | DDAH1NPC1RAB9ABCHEALDH1A1 | |
| SCHEMBL7289458 | 0.84 | DDAH1 (0.41) | DDAH1NPC1RAB9ABCHEALDH1A1 | |
| SCHEMBL9560922 | 0.82 | DDAH1 (0.51) | DDAH1NPC1RAB9ABCHETRPC3 | |
| SCHEMBL7288161 | 0.79 | EPHX2 (0.46) | DDAH1NPC1RAB9ABCHEALDH1A1 | |
| SCHEMBL7288152 | 0.79 | NPC1 (0.43) | DDAH1NPC1RAB9ABCHEALDH1A1 | |
| SCHEMBL9439979 | 0.79 | DDAH1 (0.43) | DDAH1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL10867335 | 0.78 | ACHE (0.50) | DDAH1NPC1RAB9ABCHEALDH1A1 | |
| SCHEMBL9509188 | 0.77 | RAB9A (0.54) | NPC1RAB9AALDH1A1SMN1; SMN2DAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5330982-A | Promote gastric emptying | GLAXO GROUP LIMITED (GB) | 1994-07-19 | — | — | US | disclosed |
| EP-0272876-B1 | USE OF HETEROCYCLIC DERIVATIVES FOR THE MANUFACTURE OF MEDICAMENTS | GLAXO GROUP LIMITED (GB) | 1993-10-13 | — | — | EP | disclosed |
| EP-0272876-A2 | Use of heterocyclic derivatives for the manufacture of medicaments | GLAXO GROUP LIMITED (GB) | 1988-06-29 | — | — | EP | disclosed |