Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.44 |
| ▸ | PARK7 | Q99497 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7280877 | 0.94 | ALDH1A1 (0.40) | ALDH1A1ALDH2ALDH3A1PARK7TP53 | |
| SCHEMBL7287349 | 0.82 | MAPT (0.41) | ALDH1A1TP53SMN1; SMN2SLC5A2MAPT | |
| SCHEMBL7288496 | 0.81 | GRM2 (0.40) | CA2CA9SLC5A2PTGDR2LMNA | |
| SCHEMBL7281540 | 0.79 | NLRP3 (0.41) | ALDH1A1TP53SMN1; SMN2CA2CA9 | |
| SCHEMBL7291581 | 0.79 | SCN9A (0.43) | ALDH1A1TP53CA2CA9PTGDR2 | |
| SCHEMBL10427989 | 0.78 | CA12 (0.39) | SMN1; SMN2CA2CA9PTGDR2LMNA | |
| SCHEMBL7278698 | 0.77 | ALDH1A1 (0.45) | ALDH1A1ALDH2ALDH3A1PARK7CA2 | |
| SCHEMBL9488302 | 0.77 | DRD2 (0.40) | ALDH1A1ALDH2ALDH3A1PARK7TP53 | |
| Hydrochloric Acid SCHEMBL7288578 | 0.77 | ALDH1A1 (0.44) | ALDH1A1ALDH2ALDH3A1PARK7CA2 | |
| Hydrochloric Acid SCHEMBL7290990 | 0.77 | ELANE (0.43) | ALDH1A1ALDH2ALDH3A1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313393-B1 | Benzoxazine compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4892872-A | ANTIEMETICS, ANTINAUSEA | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-01-09 | — | — | US | disclosed |
| EP-0313393-A2 | Benzoxazine compounds and pharmaceutical use thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-04-26 | — | — | EP | disclosed |