Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD5 | P21918 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288031 | 0.89 | HTR1A (0.54) | DRD2DRD3DRD4HTR7MPO | |
| SCHEMBL7288569 | 0.88 | DRD2 (0.49) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL7279846 | 0.86 | HTR1A (0.60) | DRD2DRD3DRD4HTR7HTR1A | |
| SCHEMBL7281958 | 0.86 | HTR1A (0.46) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL7282326 | 0.85 | HTR1A (0.47) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL7282164 | 0.85 | HTR1A (0.58) | DRD2DRD3DRD4HTR7HTR1A | |
| SCHEMBL7289420 | 0.85 | MPO (0.64) | DRD2HTR7MPOHTR1A | |
| SCHEMBL7280976 | 0.85 | DRD2 (0.50) | DRD2DRD3DRD4HTR1A | |
| SCHEMBL7282130 | 0.85 | CYP1A2 (0.60) | DRD2DRD3DRD4HTR7HTR1A | |
| SCHEMBL7281848 | 0.83 | HTR1A (0.64) | DRD2DRD3DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114603-A1 | Indole derivatives | MERCK PATENT GmbH (DE) | 1984-08-01 | — | — | EP | disclosed |