Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 6/20 | 0.51 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.49 |
| ▸ | ANPEP | P15144 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29701255 | 0.87 | SLC6A2 (0.63) | RENLNPEPANPEPSLC6A2AGTR1 | |
| SCHEMBL29966464 | 0.86 | LNPEP (0.49) | LNPEPANPEPSLC6A2AGTR1AGTR2 | |
| SCHEMBL30368139 | 0.85 | REN (0.53) | RENLNPEPANPEPSLC6A2AGTR1 | |
| SCHEMBL10066200 | 0.84 | AGTR1 (0.62) | RENLNPEPANPEPSLC6A2AGTR1 | |
| SCHEMBL29701316 | 0.84 | ACE (0.49) | SLC6A2OPRM1OPRD1OPRK1ACE | |
| SCHEMBL29524174 | 0.83 | F2 (0.60) | RENSLC6A2AGTR1AGTR2OPRM1 | |
| SCHEMBL30670298 | 0.83 | AGTR1 (0.62) | LNPEPANPEPSLC6A2AGTR1AGTR2 | |
| SCHEMBL11212701 | 0.83 | AGTR1 (0.54) | LNPEPANPEPSLC6A2AGTR1AGTR2 | |
| SCHEMBL11212707 | 0.83 | AGTR1 (0.54) | LNPEPANPEPSLC6A2AGTR1AGTR2 | |
| SCHEMBL29655296 | 0.83 | NTSR2 (0.58) | RENLNPEPAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225528-A | Controlling premature labor | MERCK & CO., INC. (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0444898-A1 | Cyclic hexapeptide oxytocin antagonists | MERCK & CO. INC. (US) | 1991-09-04 | — | — | EP | disclosed |