Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 2/20 | 0.57 |
| ▸ | FNTB | P49356 | 2/20 | 0.57 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7293127 | 1.00 | FNTA (0.57) | FNTAFNTBMMENPSR1ALDH1A1 | |
| SCHEMBL7302528 | 0.74 | FNTA (0.47) | FNTAFNTBMMEALDH1A1 | |
| SCHEMBL7302194 | 0.73 | MMP1 (0.55) | MME | |
| SCHEMBL7358632 | 0.73 | PPID (0.51) | FNTAFNTBALDH1A1 | |
| SCHEMBL9830756 | 0.72 | ITGA4 (0.53) | FNTAFNTBNPSR1ALDH1A1 | |
| SCHEMBL9830761 | 0.72 | ITGA4 (0.53) | FNTAFNTBNPSR1ALDH1A1 | |
| SCHEMBL7325684 | 0.71 | MME (0.55) | MME | |
| SCHEMBL1158031 | 0.71 | CA2 (0.69) | FNTAFNTBNPSR1ALDH1A1 | |
| SCHEMBL1158033 | 0.71 | CA2 (0.69) | FNTAFNTBNPSR1ALDH1A1 | |
| SCHEMBL9461939 | 0.71 | CA2 (0.69) | FNTAFNTBNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516980-B1 | Novel 2-mercaptomethylene-tetrahydronaphthalene and indane-2-carboxamide derivatives as enkephalinase inhibitors | MERRELL PHARMA INC (US) | 1996-04-17 | — | — | EP | disclosed |