Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294567 | 0.86 | MME (0.57) | MMEMMP1 | |
| SCHEMBL7294573 | 0.86 | MME (0.57) | MMEMMP1 | |
| SCHEMBL7302194 | 0.85 | MMP1 (0.55) | MMEMMP1 | |
| SCHEMBL7294113 | 0.84 | ALDH1A1 (0.41) | FNTAFNTBMMEALDH1A1 | |
| SCHEMBL7293268 | 0.84 | MME (0.48) | FNTAFNTBMMEALDH1A1MMP1 | |
| SCHEMBL7292661 | 0.75 | MME (0.55) | MMEMMP1 | |
| SCHEMBL7293127 | 0.74 | FNTA (0.57) | FNTAFNTBMMEALDH1A1 | |
| SCHEMBL7293136 | 0.74 | FNTA (0.57) | FNTAFNTBMMEALDH1A1 | |
| SCHEMBL7294105 | 0.74 | MME (0.82) | MME | |
| SCHEMBL7294452 | 0.72 | MME (0.61) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516980-B1 | Novel 2-mercaptomethylene-tetrahydronaphthalene and indane-2-carboxamide derivatives as enkephalinase inhibitors | MERRELL PHARMA INC (US) | 1996-04-17 | — | — | EP | disclosed |
| US-5252601-A | 2-mercaptomethylene-tetrahydronaphthalene and indane-2-carboxamide derivatives as enkephalinase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0516980-A1 | Novel 2-mercaptomethylene-tetrahydronaphthalene and indane-2-carboxamide derivatives as enkephalinase inhibitors | MERRELL PHARMACEUTICALS INC. (US) | 1992-12-09 | — | — | EP | disclosed |