Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | GLS2 | Q9UI32 | 3/20 | 0.35 |
| ▸ | PDCD4 | Q53EL6 | 2/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325034 | 0.84 | GLS2 (0.35) | GLS2PDCD4LTB4RFAAHALDH1A1 | |
| SCHEMBL7295059 | 0.84 | GLS2 (0.35) | GLS2PDCD4LTB4RFAAHALDH1A1 | |
| SCHEMBL9670950 | 0.84 | GLS2 (0.35) | GLS2PDCD4LTB4RFAAHALDH1A1 | |
| SCHEMBL9671037 | 0.84 | GLS2 (0.35) | GLS2PDCD4LTB4RFAAHALDH1A1 | |
| Benzene SCHEMBL9326381 | 0.82 | ALDH1A1 (0.36) | GLS2PDCD4LTB4RALDH1A1 | |
| SCHEMBL9671361 | 0.79 | SIGMAR1 (0.35) | ALDH1A1 | |
| SCHEMBL10431816 | 0.75 | PRKCA (0.34) | LTA4H | |
| SCHEMBL9671527 | 0.75 | CA2 (0.40) | LTB4RALDH1A1 | |
| SCHEMBL7301168 | 0.75 | CA2 (0.40) | LTB4RALDH1A1 | |
| SCHEMBL7303995 | 0.75 | CA2 (0.40) | LTB4RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5376676-A | Process of using anti-inflammatory furanones as selective calcium channel inhibitors | ALLERGAN, INC. (US) | 1994-12-27 | — | — | US | disclosed |
| US-5134128-A | Immunosuppressive and antiproliferative activity for psoriasis and calcium homeostasis | ALLERGAN, INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-5045564-A | Calcium channel antagonists | ALLERGAN, INC. (US) | 1991-09-03 | — | — | US | disclosed |
| EP-0372941-A2 | Anti-inflammatory 5-hydroxy-2-furanones | ALLERGAN, INC (US) | 1990-06-13 | — | — | EP | disclosed |
| EP-0372940-A2 | Anti-inflammatory 2-furanones | ALLERGAN, INC (US) | 1990-06-13 | — | — | EP | disclosed |