Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | PHGDH | O43175 | 1/20 | 0.60 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 2/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ATM | Q13315 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302107 | 0.90 | NPC1 (0.69) | NPC1RAB9AMAPK1SMN1; SMN2GAA | |
| SCHEMBL6171612 | 0.82 | RAB9A (0.65) | NPC1RAB9AMAPK1SMN1; SMN2GAA | |
| SCHEMBL6169544 | 0.81 | NPC1 (0.78) | NPC1RAB9AMAPK1SMN1; SMN2GAA | |
| SCHEMBL7303587 | 0.81 | RAB9A (0.68) | NPC1RAB9ASMN1; SMN2SERPINE1ALDH1A1 | |
| SCHEMBL7300373 | 0.80 | RAB9A (0.58) | NPC1RAB9AMAPK1SMN1; SMN2GAA | |
| SCHEMBL7292066 | 0.80 | KCNMA1 (0.69) | NPC1RAB9ASMN1; SMN2SERPINE1ALDH1A1 | |
| SCHEMBL4129918 | 0.80 | L3MBTL1 (0.54) | RAB9AMAPK1ALDH1A1HTTLMNA | |
| SCHEMBL7293409 | 0.80 | SERPINE1 (0.67) | NPC1RAB9ASMN1; SMN2GAASERPINE1 | |
| SCHEMBL7302295 | 0.79 | SERPINE1 (0.65) | NPC1RAB9ASMN1; SMN2GAASERPINE1 | |
| SCHEMBL7297665 | 0.78 | SERPINE1 (0.72) | NPC1RAB9ASMN1; SMN2GAASERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |