Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7298224 | 0.87 | F10 (0.47) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9269317 | 0.86 | F10 (0.46) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7297516 | 0.82 | ST14 (0.64) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7118598 | 0.80 | ITGB3 (0.74) | ITGB3ITGA2BST14F2F10 | |
| SCHEMBL7304057 | 0.80 | ITGB3 (0.56) | ITGB3ITGA2BTPSAB1EPHX2NR1H4 | |
| SCHEMBL7298011 | 0.80 | ITGB3 (0.57) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9271862 | 0.79 | ITGB3 (0.55) | ITGB3ITGA2BTPSAB1EPHX2NR1H4 | |
| SCHEMBL9452086 | 0.74 | NPC1 (0.46) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7302955 | 0.73 | ALDH1A1 (0.47) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9270045 | 0.72 | ST14 (0.54) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381033-B1 | Carboxylic-acid and sulphonic-acid amides | HOFFMANN LA ROCHE (CH) | 1994-03-23 | — | — | EP | claimed |
| US-5256812-A | Antitumor agents, cardiovascular disorders; having amidino or guandino groups | HOFFMANN-LA ROCHE INC. (US) | 1993-10-26 | — | — | US | claimed |
| US-5399585-A | Anitcoagulants, antiinflammatory, antitumor | HOFFMANN-LA ROCHE INC. (US) | 1995-03-21 | — | — | US | disclosed |
| US-5256812-A | Antitumor agents, cardiovascular disorders; having amidino or guandino groups | HOFFMANN-LA ROCHE INC. (US) | 1993-10-26 | — | — | US | disclosed |
| US-5084466-A | Anticoagulants, antiinflammatory agents, atheriosclerosis and antitumor agents | HOFFMANN-LA ROCHE INC. (US) | 1992-01-28 | — | — | US | disclosed |