Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | F10 | P00742 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.48 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9271862 | 0.99 | ITGB3 (0.55) | ITGB3ITGA2BF2F10EPHX2 | |
| SCHEMBL7297516 | 0.86 | ST14 (0.64) | ITGB3ITGA2BF2EPHX2NR1H4 | |
| SCHEMBL7296789 | 0.86 | ITGB3 (0.50) | ITGB3ITGA2BF2F10ST14 | |
| Hydrochloric Acid SCHEMBL9269810 | 0.85 | ITGB3 (0.49) | ITGB3ITGA2BF2F10ST14 | |
| SCHEMBL7118598 | 0.84 | ITGB3 (0.74) | ITGB3ITGA2BF2F10ST14 | |
| SCHEMBL7296103 | 0.80 | ITGB3 (0.52) | ITGB3ITGA2BF2F10EPHX2 | |
| SCHEMBL7294121 | 0.78 | ITGB3 (0.67) | ITGB3ITGA2BF2F10EPHX2 | |
| SCHEMBL7373439 | 0.76 | PPARG (0.70) | ITGB3ITGA2BF2F10EPHX2 | |
| SCHEMBL7380405 | 0.76 | F10 (0.58) | ITGB3ITGA2BF2F10ST14 | |
| SCHEMBL9335737 | 0.75 | TPSAB1 (0.67) | ITGB3ITGA2BF2EPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381033-B1 | Carboxylic-acid and sulphonic-acid amides | HOFFMANN LA ROCHE (CH) | 1994-03-23 | — | — | EP | claimed |
| US-5256812-A | Antitumor agents, cardiovascular disorders; having amidino or guandino groups | HOFFMANN-LA ROCHE INC. (US) | 1993-10-26 | — | — | US | claimed |