Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300717 | 0.81 | TRPA1 (0.31) | TRPA1TSHR | |
| SCHEMBL7290538 | 0.77 | HTR2C (0.33) | — | |
| SCHEMBL7299115 | 0.76 | PKM (0.32) | — | |
| SCHEMBL7300100 | 0.76 | — | — | |
| SCHEMBL7298705 | 0.76 | HTR2C (0.32) | — | |
| SCHEMBL7292477 | 0.75 | TSHR (0.32) | TRPA1TSHRKDM4EALDH1A1 | |
| SCHEMBL7298538 | 0.73 | KDM4E (0.33) | KDM4EALDH1A1 | |
| SCHEMBL7298521 | 0.72 | KMT2A (0.32) | — | |
| SCHEMBL7299153 | 0.70 | TSHR (0.32) | TRPA1TSHR | |
| SCHEMBL7300190 | 0.69 | TRPA1 (0.36) | TRPA1TSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260444-A | Cardiovascular, hypotensive | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-11-09 | — | — | US | disclosed |
| US-5208245-A | Hypotensive agents | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-05-04 | — | — | US | disclosed |
| EP-0460418-A2 | Novel Dihydropyridine derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-12-11 | — | — | EP | disclosed |