Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299156 | 0.81 | TRPA1 (0.33) | TRPA1TSHR | |
| SCHEMBL7294345 | 0.78 | — | — | |
| SCHEMBL9585033 | 0.72 | TDP1 (0.37) | TSHR | |
| SCHEMBL7298874 | 0.69 | KCNE1 (0.39) | — | |
| SCHEMBL7300190 | 0.66 | TRPA1 (0.36) | TRPA1TSHR | |
| SCHEMBL9584210 | 0.64 | TRPA1 (0.35) | TRPA1TSHR | |
| SCHEMBL7301411 | 0.60 | TRPV1 (0.33) | — | |
| SCHEMBL7292477 | 0.60 | TSHR (0.32) | TRPA1TSHR | |
| SCHEMBL7297848 | 0.60 | KCNE1 (0.35) | — | |
| SCHEMBL18744648 | 0.58 | CA2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260444-A | Cardiovascular, hypotensive | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-11-09 | — | — | US | disclosed |
| US-5208245-A | Hypotensive agents | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-05-04 | — | — | US | disclosed |
| EP-0460418-A2 | Novel Dihydropyridine derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-12-11 | — | — | EP | disclosed |