Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 3/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10487896 | 0.86 | MAPT (0.57) | HSD17B10KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL7306990 | 0.86 | KDM4E (0.49) | HSD17B10KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL7308089 | 0.83 | TNF (0.62) | HSD17B10KDM4EMAPTTNF | |
| SCHEMBL7310111 | 0.82 | MAOA (0.46) | HSD17B10KDM4EKMT2AMEN1MAPT | |
| SCHEMBL7649974 | 0.80 | MAPK10 (0.55) | HSD17B10KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL7298112 | 0.79 | MAOA (0.46) | HSD17B10KDM4EKMT2AMEN1MAPT | |
| SCHEMBL14266806 | 0.79 | PLA2G2A (0.50) | HSD17B10KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL7309296 | 0.79 | TDP1 (0.47) | HSD17B10KDM4EALDH1A1ALOX15TNF | |
| SCHEMBL10487880 | 0.77 | ALDH1A1 (0.49) | HSD17B10KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL355062 | 0.77 | PSEN1 (0.54) | HSD17B10KDM4EKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481342-A1 | Quinazoline derivatives and their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |