Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660613 | 0.86 | ALDH1A1 (0.49) | TDP1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7308089 | 0.84 | TNF (0.62) | HSD17B10TNFLMNAKDM4EGAA | |
| SCHEMBL7301671 | 0.83 | MAT2A (0.48) | ALDH1A1HSD17B10KDM4EGAAHPGD | |
| SCHEMBL7026263 | 0.79 | ALDH1A1 (0.48) | TDP1ALDH1A1LMNAKDM4EL3MBTL1 | |
| SCHEMBL7300323 | 0.79 | HSD17B10 (0.48) | ALDH1A1ALOX15TSHRHSD17B10TNF | |
| SCHEMBL7651696 | 0.78 | MAT2A (0.44) | MAT2A | |
| SCHEMBL7309368 | 0.78 | MAT2A (0.44) | ALDH1A1HPGDMAT2A | |
| SCHEMBL7302539 | 0.77 | MAT2A (0.44) | MAT2A | |
| SCHEMBL10487968 | 0.77 | ALDH1A1 (0.52) | TDP1ALDH1A1ALOX15TSHRHSD17B10 | |
| SCHEMBL8432918 | 0.76 | CBX7 (0.47) | ALDH1A1LMNAKDM4EEGFRMAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481342-A1 | Quinazoline derivatives and their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |