Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7331153 | 0.93 | HDAC6 (0.53) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7305313 | 0.90 | HDAC6 (0.49) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7306359 | 0.86 | PRSS1 (0.46) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8407335 | 0.86 | HTT (0.60) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7296073 | 0.81 | ITGB3 (0.43) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7298211 | 0.80 | ITGB3 (0.43) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7305875 | 0.80 | ACE (0.49) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8409954 | 0.80 | MAPT (0.48) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9335659 | 0.79 | HDAC1 (0.48) | HDAC6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7305320 | 0.79 | HDAC6 (0.45) | HDAC6HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445796-A2 | Derivatives of acetic acid | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-11 | — | — | EP | disclosed |