Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7293357 | 0.79 | ALDH1A1 (0.33) | TRPV1HTR2C | |
| SCHEMBL7300510 | 0.73 | CYP2D6 (0.33) | — | |
| SCHEMBL7301451 | 0.70 | HTR2C (0.39) | TRPV1HTR2C | |
| SCHEMBL7301411 | 0.69 | TRPV1 (0.33) | TRPV1HTR2C | |
| SCHEMBL2318975 | 0.68 | TRPM8 (0.41) | TRPV1 | |
| SCHEMBL3323531 | 0.67 | TRPV1 (0.43) | TRPV1HTR2C | |
| SCHEMBL3323535 | 0.67 | TRPV1 (0.43) | TRPV1HTR2C | |
| SCHEMBL9583848 | 0.64 | HTR2C (0.33) | HTR2C | |
| SCHEMBL7299199 | 0.62 | ADRA2A (0.33) | — | |
| SCHEMBL7294341 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260444-A | Cardiovascular, hypotensive | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-11-09 | — | — | US | disclosed |
| US-5208245-A | Hypotensive agents | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-05-04 | — | — | US | disclosed |
| EP-0460418-A2 | Novel Dihydropyridine derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-12-11 | — | — | EP | disclosed |