Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288889 | 0.81 | ADRA2A (0.33) | ADRA2A | |
| SCHEMBL7298271 | 0.77 | NOTUM (0.37) | ADRA2A | |
| SCHEMBL9584408 | 0.77 | ADRA2A (0.33) | ADRA2A | |
| SCHEMBL7312064 | 0.77 | TAAR1 (0.31) | — | |
| SCHEMBL7301421 | 0.73 | TRPA1 (0.33) | — | |
| SCHEMBL3111326 | 0.71 | DRD2 (0.33) | — | |
| SCHEMBL7298111 | 0.70 | TDP1 (0.40) | — | |
| SCHEMBL5551681 | 0.69 | ADRB1 (0.41) | — | |
| SCHEMBL7290875 | 0.69 | ITGB2 (0.38) | — | |
| SCHEMBL433176 | 0.67 | ITGB2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260444-A | Cardiovascular, hypotensive | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-11-09 | — | — | US | disclosed |
| US-5208245-A | Hypotensive agents | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-05-04 | — | — | US | disclosed |
| EP-0460418-A2 | Novel Dihydropyridine derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-12-11 | — | — | EP | disclosed |