Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30879601 | 0.88 | HIF1A (0.57) | HIF1AFOLH1ALDH1A1ALOX15HPGD | |
| SCHEMBL18586492 | 0.84 | FOLH1 (0.42) | HIF1AFOLH1ALDH1A1ALOX15HPGD | |
| SCHEMBL13320279 | 0.81 | HIF1A (0.51) | HIF1AFOLH1ALDH1A1ALOX15HPGD | |
| SCHEMBL16701894 | 0.81 | PKM (0.58) | HIF1AFOLH1ALDH1A1ALOX15HPGD | |
| SCHEMBL8991903 | 0.79 | ALDH1A1 (0.44) | HIF1AALDH1A1ALOX15HPGDTSHR | |
| SCHEMBL14793752 | 0.79 | AKR1B1 (0.53) | HIF1ATSHRKDM4EBCAT2RAB9A | |
| SCHEMBL2875329 | 0.79 | TSHR (0.67) | HIF1ATSHRHSD17B10KDM4E | |
| SCHEMBL31126963 | 0.79 | HIF1A (0.53) | HIF1AFOLH1ALDH1A1ALOX15HPGD | |
| SCHEMBL5780166 | 0.78 | HIF1A (0.43) | HIF1AFOLH1ALDH1A1TSHRHTT | |
| SCHEMBL6366958 | 0.78 | TSHR (0.64) | HIF1ATSHRHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428009-A | Antibiotics, fungicides, and antiprotozoa agents | MERCK & CO., INC. (US) | 1995-06-27 | — | — | US | disclosed |
| US-5385884-A | Water-soluble, injectible echinocandins; fungicides; antiprotozoa agents, yeasts | MERCK & CO. INC. (US) | 1995-01-31 | — | — | US | disclosed |
| US-5369093-A | Antibiotic lipopeptides as fungicides and antiprotozoa agents | MERCK & CO., INC. (US) | 1994-11-29 | — | — | US | disclosed |
| US-5330973-A | Fungicides, antiprotozoa agents | MERCK & CO., INC. (US) | 1994-07-19 | — | — | US | disclosed |
| EP-0503960-A1 | Cyclic lipopeptides having antibiotic activity | MERCK & CO. INC. (US) | 1992-09-16 | — | — | EP | disclosed |
| EP-0448354-A2 | Lipopeptide derivatives | MERCK & CO. INC. (US) | 1991-09-25 | — | — | EP | disclosed |
| EP-0448343-A2 | Lipopeptide derivatives | MERCK & CO. INC. (US) | 1991-09-25 | — | — | EP | disclosed |