SCHEMBL2875329

SCHEMBL2875329

O=C(O)CNCc1ccccc1O

nearest known ligand 0.67

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.67
HIF1A Q16665 2/20 0.67
CYP2D6 P10635 1/20 0.67
CA12 O43570 6/20 0.62
CA2 P00918 6/20 0.62
PKM P14618 1/20 0.59
AKR1B1 P15121 1/20 0.59
CA9 Q16790 5/20 0.58
KDM4E B2RXH2 1/20 0.58
HSD17B10 Q99714 1/20 0.58
MPO P05164 6/20 0.56
SLC6A4 P31645 1/20 0.53
NOX4 Q9NPH5 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6366958 0.98 TSHR (0.64) TSHRHIF1ACYP2D6CA12CA2
SCHEMBL3200193 0.85 CA12 (0.69) TSHRHIF1ACYP2D6CA12CA2
SCHEMBL4783666 0.83 TSHR (0.64) TSHRHIF1ACYP2D6CA12CA2
SCHEMBL6366954 0.81 TSHR (0.62) TSHRHIF1ACYP2D6CA12CA2
SCHEMBL2595163 0.81 MPO (0.62) TSHRHIF1ACYP2D6CA12CA2
SCHEMBL28133911 0.81 CA12 (0.74) TSHRHIF1ACYP2D6CA12CA2
SCHEMBL28044791 0.81 HIF1A (0.59) TSHRHIF1ACYP2D6CA12CA2
SCHEMBL460754 0.81 TSHR (1.00) TSHRHIF1ACYP2D6CA12CA2
SCHEMBL8991903 0.81 ALDH1A1 (0.44) TSHRHIF1ACYP2D6AKR1B1KDM4E
SCHEMBL14793752 0.81 AKR1B1 (0.53) TSHRHIF1ACYP2D6AKR1B1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5844012-A Process and composition for improving the cure of water-blown molded polyurethane foam AIR PRODUCTS AND CHEMICALS, INC. (US) 1998-12-01 US claimed
US-4091088-A Phenolic amino-carboxylic acid complexes for forming radiopharmaceuticals AUSTRALIAN ATOMIC ENERGY COMMISSION (AU) 1978-05-23 US claimed
US-4088747-A Phenolic amino-carboxylic acid radiopharmaceuticals AUSTRALIAN ATOMIC ENERGY COMMISSION (AU) 1978-05-09 US claimed
JP-11255632-A None JP disclosed
US-20260132160-A1 IRON REPLACEMENT TREATMENTS THE GENERAL HOSPITAL CORP (US) 2026-05-14 US disclosed
EP-4604943-A2 IRON REPLACEMENT TREATMENTS The General Hospital Corporation (US) 2025-08-27 EP disclosed
WO-2024086535-A2 IRON REPLACEMENT TREATMENTS THE GENERAL HOSPITAL CORPORATION (US) 2024-04-25 WO disclosed
CN-112805312-B Catalyst for PIR/PUR foam production 亨茨曼国际有限公司 2023-03-21 CN disclosed
EP-3848349-B1 A PROCESS FOR THE PREPARATION OF SALTS OF N,N'-DISUBSTITUTED ETHYLENEDIAMINE-N,N'-DIACETIC ACID DERIVATIVES AND THEIR USE PRZED PRODUKCYJNO CONSULTINGOWE ADOB SP Z O O (PL) 2023-03-15 EP disclosed
WO-2022148843-A1 COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF 3B PHARMACEUTICALS GMBH (DE) 2022-07-14 WO disclosed
EP-3848349-A1 A PROCESS FOR THE PREPARATION OF SALTS OF N,N'-DISUBSTITUTED ETHYLENEDIAMINE-N,N'-DIACETIC ACID DERIVATIVES AND THEIR USE Przedsiebiorstwo Produkcyjno-Consultingowe ADOB Sp. z o.o. Sp. jawna (PL) 2021-07-14 EP disclosed
US-4256802-A BLENDING A POLYISOCYANATE AND AN AMINE DIOL MISCIBLE WITH THE FLUOROCARBON BLOWING AGENTS AND TRIMERIZATION CATALYST; LAMINATION; INSULATION THE UPJOHN COMPANY (US) 1981-03-17 US disclosed
US-4246364-A USEFUL AS LAMINATES THE UPJOHN COMPANY (US) 1981-01-20 US disclosed
US-4126742-A High-modulus polyisocyanurate elastomers THE UPJOHN COMPANY (US) 1978-11-21 US disclosed
US-4126741-A High-modulus polyisocyanurate elastomers THE UPJOHN COMPANY (US) 1978-11-21 US disclosed
US-4011180-A NOVEL COCATALYST SYSTEM FOR TRIMERIZING POLYISOCYANATES THE UPJOHN COMPANY (US) 1977-03-08 US disclosed
US-4011180-A NOVEL COCATALYST SYSTEM FOR TRIMERIZING POLYISOCYANATES THE UPJOHN COMPANY (US) 1977-03-08 US disclosed
US-3986991-A EPOXIDES, TERTIARY AMINE, GLYCINE SALT THE UPJOHN COMPANY (US) 1976-10-19 US disclosed
US-3986991-A EPOXIDES, TERTIARY AMINE, GLYCINE SALT THE UPJOHN COMPANY (US) 1976-10-19 US disclosed
US-3903018-A Novel cocatalyst system for trimerizing polyisocyanates DOW CHEMICAL COMPANY, THE 1975-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132160-A1 IRON REPLACEMENT TREATMENTS TFRC, SLC40A1, FTH1 TSHR 39/4885HIF1A 353/4885CYP2D6 1393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.