Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3200509 | 0.85 | S1PR5 (0.53) | ALDH1A1TSHRS1PR5KDM4EHPGD | |
| SCHEMBL14793752 | 0.85 | AKR1B1 (0.53) | NR4A2TSHRHIF1ACYP2D6PTGS2 | |
| SCHEMBL8991883 | 0.83 | ALDH1A1 (0.57) | ALDH1A1HTTAKR1B1KDM4EMEN1 | |
| SCHEMBL906143 | 0.81 | TSHR (0.52) | ALDH1A1HTTTSHRHIF1ACYP2D6 | |
| SCHEMBL2875329 | 0.81 | TSHR (0.67) | TSHRHIF1ACYP2D6AKR1B1KDM4E | |
| SCHEMBL7301923 | 0.79 | HIF1A (0.51) | ALDH1A1HTTNR4A2TSHRHIF1A | |
| SCHEMBL27406485 | 0.79 | RAB9A (0.59) | ALDH1A1CYP2D6KDM4ECYP2C19MEN1 | |
| SCHEMBL5971823 | 0.79 | NR4A2 (0.41) | ALDH1A1NR4A2TSHRHIF1ACYP2D6 | |
| SCHEMBL6366958 | 0.79 | TSHR (0.64) | TSHRHIF1ACYP2D6AKR1B1KDM4E | |
| SCHEMBL16702802 | 0.79 | KMT2A (0.53) | ALDH1A1KDM4EMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527882-A | BRADYKININ | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-06-18 | — | — | US | disclosed |