Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7647926 | 0.82 | KMT2A (0.55) | MEN1KMT2AHPGDPOLBGAA | |
| SCHEMBL6609282 | 0.81 | MEN1 (1.00) | MEN1KMT2AHPGDSIRT6MAPT | |
| SCHEMBL4336239 | 0.78 | L3MBTL3 (0.69) | MEN1KMT2ASIRT6MAPTPOLB | |
| SCHEMBL4191910 | 0.78 | SIRT6 (0.72) | MEN1KMT2ASIRT6MAPTPOLB | |
| SCHEMBL77340 | 0.77 | MAPT (0.71) | MEN1KMT2ASIRT6MAPTPOLB | |
| SCHEMBL3574460 | 0.77 | MAPT (0.71) | MEN1KMT2ASIRT6MAPTPOLB | |
| SCHEMBL7301802 | 0.76 | TRPV6 (0.59) | MEN1KMT2AMAPTPOLBCYP2C9 | |
| SCHEMBL521556 | 0.76 | KMT2A (0.64) | MEN1KMT2ASIRT6MAPTPOLB | |
| SCHEMBL17797589 | 0.76 | PNMT (0.47) | MEN1KMT2AMAPTPOLBRAB9A | |
| SCHEMBL30612409 | 0.76 | AKR1C3 (0.45) | MEN1KMT2AMAPTPOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503411-B1 | Substituted N-phenylpiperidines and medicaments thereof | BASF AG (DE) | 1995-11-29 | — | — | EP | disclosed |
| US-5296485-A | Substituted N-phenylpiperidines and drugs therefrom | BASF AKTIENGESELLSCHAFT (DE) | 1994-03-22 | — | — | US | disclosed |