Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.58 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ESRRB | O95718 | 1/20 | 0.47 |
| ▸ | ESRRG | P62508 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL241159 | 0.91 | DHFR (0.50) | SLC18A3L3MBTL1GRIN2BKMT2ASMN1; SMN2 | |
| SCHEMBL7302753 | 0.85 | SLC18A3 (0.58) | SLC18A3L3MBTL3L3MBTL1MBTD1GRIN2B | |
| SCHEMBL16763481 | 0.84 | SLC18A3 (0.47) | SLC18A3L3MBTL3L3MBTL1MBTD1GRIN2B | |
| SCHEMBL29449720 | 0.82 | MAPT (0.53) | SLC18A3L3MBTL3L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL6613474 | 0.81 | SMPD3 (0.47) | SLC18A3L3MBTL1CYP2C19HPGDKMT2A | |
| SCHEMBL7301802 | 0.80 | TRPV6 (0.59) | SLC18A3L3MBTL3L3MBTL1MBTD1GRIN2B | |
| SCHEMBL2236451 | 0.79 | L3MBTL3 (0.81) | L3MBTL3L3MBTL1MBTD1KMT2AKDM4E | |
| SCHEMBL3515888 | 0.79 | SLC18A3 (0.60) | SLC18A3GRIN2BCYP2D6CYP2C19ESRRB | |
| SCHEMBL7446491 | 0.79 | MBTD1 (0.55) | SLC18A3L3MBTL3L3MBTL1MBTD1GRIN2B | |
| SCHEMBL2965273 | 0.79 | SLC18A3 (0.81) | SLC18A3GRIN2BCYP2D6CYP2C19HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503411-B1 | Substituted N-phenylpiperidines and medicaments thereof | BASF AG (DE) | 1995-11-29 | — | — | EP | disclosed |
| US-5296485-A | Substituted N-phenylpiperidines and drugs therefrom | BASF AKTIENGESELLSCHAFT (DE) | 1994-03-22 | — | — | US | disclosed |