Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 4/20 | 0.44 |
| ▸ | JAK3 | P52333 | 2/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451750 | 0.92 | LSS (0.47) | JAK2JAK3MCHR1LSSHDAC1 | |
| Hydrochloric Acid SCHEMBL7307376 | 0.88 | MCHR1 (0.53) | MCHR1LSSADRB2ADRB1ADRB3 | |
| SCHEMBL9451668 | 0.83 | MAPT (0.46) | MCHR1LSSALDH1A1MAPT | |
| SCHEMBL9451687 | 0.82 | MCHR1 (0.57) | JAK2JAK3MCHR1HDAC1ADRB2 | |
| SCHEMBL9451561 | 0.81 | DRD3 (0.46) | JAK2JAK3MCHR1LSSKDM4E | |
| SCHEMBL10680323 | 0.78 | JAK2 (0.50) | JAK2JAK3ALDH1A1ADRB2ADRB1 | |
| SCHEMBL2321959 | 0.76 | ADRB1 (0.45) | JAK2JAK3HDAC1KDM4EALDH1A1 | |
| SCHEMBL7296078 | 0.76 | LSS (0.43) | JAK2JAK3LSSKDM4EALDH1A1 | |
| SCHEMBL7319744 | 0.76 | KDM4E (0.48) | JAK2JAK3KDM4EADRB2ADRB1 | |
| SCHEMBL9828313 | 0.75 | JAK2 (0.47) | JAK2JAK3HDAC1ALDH1A1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481299-B1 | N-phenyl-piperidyl-4-amines and drugs containing them | BASF AG (DE) | 1994-07-20 | — | — | EP | disclosed |
| EP-0481299-A2 | N-phenyl-piperidyl-4-amines and drugs containing them | BASF Aktiengesellschaft (DE) | 1992-04-22 | — | — | EP | disclosed |