Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.57 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 5/20 | 0.44 |
| ▸ | JAK3 | P52333 | 2/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7307376 | 0.83 | MCHR1 (0.53) | MCHR1ADRB1ADRB2ADRB3RORC | |
| SCHEMBL9451750 | 0.82 | LSS (0.47) | MCHR1JAK2JAK3ADRB1ADRB2 | |
| SCHEMBL7302740 | 0.82 | JAK2 (0.44) | MCHR1JAK2JAK3ADRB1ADRB2 | |
| SCHEMBL9451683 | 0.77 | JAK2 (0.46) | GPR119JAK2JAK3ADRB1ADRB2 | |
| SCHEMBL9451561 | 0.76 | DRD3 (0.46) | MCHR1JAK2JAK3ADRB1ADRB2 | |
| SCHEMBL13621154 | 0.74 | KDM4E (0.57) | MCHR1 | |
| SCHEMBL9451668 | 0.74 | MAPT (0.46) | MCHR1MEN1KMT2A | |
| SCHEMBL17888208 | 0.74 | TDP1 (0.52) | MCHR1KMT2A | |
| SCHEMBL10676523 | 0.74 | GPR119 (0.62) | GPR119JAK2JAK3ADRB1ADRB2 | |
| SCHEMBL2321959 | 0.74 | ADRB1 (0.45) | GPR119JAK2JAK3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260318-A | Phenylpiperidylamines and drugs containing them | BASF AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | disclosed |