Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 14/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 12/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451750 | 0.80 | LSS (0.47) | KDM4EADRB3ADRB1ADRB2LMNA | |
| SCHEMBL9451561 | 0.78 | DRD3 (0.46) | KDM4EADRB3ADRB1ADRB2LMNA | |
| SCHEMBL7302491 | 0.77 | IGF1R (0.53) | KDM4ELMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7307376 | 0.76 | MCHR1 (0.53) | ADRB3ADRB1ADRB2 | |
| SCHEMBL10561148 | 0.76 | ADRB2 (0.62) | KDM4EADRB3ADRB1ADRB2LMNA | |
| SCHEMBL2321959 | 0.76 | ADRB1 (0.45) | KDM4EADRB3ADRB1ADRB2LMNA | |
| SCHEMBL7302740 | 0.76 | JAK2 (0.44) | KDM4EADRB3ADRB1ADRB2JAK2 | |
| SCHEMBL9309161 | 0.75 | KDM4E (0.47) | KDM4ELMNAMEN1KMT2ABLM | |
| SCHEMBL7301452 | 0.74 | JAK2 (0.64) | ADRB3ADRB1ADRB2KCNH2JAK2 | |
| SCHEMBL9451687 | 0.73 | MCHR1 (0.57) | ADRB3ADRB1ADRB2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503411-B1 | Substituted N-phenylpiperidines and medicaments thereof | BASF AG (DE) | 1995-11-29 | — | — | EP | disclosed |
| US-5296485-A | Substituted N-phenylpiperidines and drugs therefrom | BASF AKTIENGESELLSCHAFT (DE) | 1994-03-22 | — | — | US | disclosed |
| EP-0503411-A1 | Substituted N-phenylpiperidines and medicaments thereof | BASF Aktiengesellschaft (DE) | 1992-09-16 | — | — | EP | disclosed |