Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313036 | 0.95 | SIGMAR1 (0.35) | SIGMAR1HTR2BCACNA1HITGB3ITGA2B | |
| SCHEMBL7307739 | 0.95 | SIGMAR1 (0.35) | SIGMAR1HTR2BCACNA1HITGB3ITGA2B | |
| SCHEMBL7308728 | 0.93 | SIGMAR1 (0.34) | SIGMAR1HTR2BCD274 | |
| SCHEMBL7315937 | 0.92 | ITGB3 (0.35) | SIGMAR1CACNA1HITGB3ITGA2B | |
| SCHEMBL7307508 | 0.91 | SIGMAR1 (0.36) | SIGMAR1HTR2B | |
| SCHEMBL7317037 | 0.91 | DRD2 (0.33) | HTR2BITGB3ITGA2B | |
| SCHEMBL7306190 | 0.89 | GPR119 (0.32) | — | |
| SCHEMBL7304829 | 0.89 | SMN1; SMN2 (0.32) | SIGMAR1ITGB3ITGA2B | |
| SCHEMBL7306785 | 0.88 | GPR119 (0.33) | — | |
| SCHEMBL7314220 | 0.88 | SIGMAR1 (0.36) | SIGMAR1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |