Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306190 | 0.95 | GPR119 (0.32) | DRD2DRD3 | |
| SCHEMBL7306785 | 0.94 | GPR119 (0.33) | DRD2 | |
| SCHEMBL7316461 | 0.92 | DRD2 (0.34) | DRD2DRD3HTR2BRORC | |
| SCHEMBL7316825 | 0.92 | ITGB3 (0.34) | DRD2DRD3RORCITGB3ITGA2B | |
| SCHEMBL7310892 | 0.91 | DRD2 (0.33) | DRD2DRD3HTR2BITGB3ITGA2B | |
| SCHEMBL7303526 | 0.91 | SIGMAR1 (0.33) | HTR2BITGB3ITGA2B | |
| SCHEMBL7307739 | 0.89 | SIGMAR1 (0.35) | DRD2HTR2BITGB3ITGA2B | |
| SCHEMBL7313036 | 0.89 | SIGMAR1 (0.35) | DRD2HTR2BITGB3ITGA2B | |
| SCHEMBL7310067 | 0.88 | DRD2 (0.33) | DRD2DRD3JAK2JAK3PTK2 | |
| SCHEMBL7316507 | 0.88 | FAAH (0.33) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |