Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.51 |
| ▸ | LAP3 | P28838 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896358 | 0.80 | FOLH1 (0.49) | FOLH1LAP3RNPEPSLC7A5ALDH1A1 | |
| SCHEMBL8610371 | 0.80 | FOLH1 (0.49) | FOLH1LAP3RNPEPSLC7A5ALDH1A1 | |
| SCHEMBL8896352 | 0.80 | FOLH1 (0.49) | FOLH1LAP3RNPEPSLC7A5ALDH1A1 | |
| SCHEMBL8610377 | 0.80 | FOLH1 (0.49) | FOLH1LAP3RNPEPSLC7A5ALDH1A1 | |
| SCHEMBL104010 | 0.75 | ALOX15 (0.50) | CHRNB2CHRNB4CHRNA3CHRNA4BCHE | |
| SCHEMBL7308675 | 0.74 | FOLH1 (0.53) | FOLH1LAP3RNPEPSLC7A5ALDH1A1 | |
| SCHEMBL11752273 | 0.74 | CHRNB2 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4BCHE | |
| SCHEMBL7310650 | 0.73 | ALDH1A1 (0.51) | FOLH1ALDH1A1MAPT | |
| SCHEMBL19301334 | 0.73 | FOLH1 (0.50) | FOLH1LAP3RNPEPSLC7A5ALDH1A1 | |
| SCHEMBL11419405 | 0.72 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |