Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308900 | 0.96 | ACHE (0.42) | ACHEBCHECHRM4DRD2DRD4 | |
| SCHEMBL7316449 | 0.95 | ACHE (0.43) | ACHEBCHECHRM4DRD2DRD4 | |
| SCHEMBL7314739 | 0.95 | ACHE (0.43) | ACHEBCHECHRM4DRD2DRD4 | |
| SCHEMBL7307268 | 0.92 | LMNA (0.40) | ACHEBCHECACNA1GDRD2DRD4 | |
| SCHEMBL7311514 | 0.92 | ACHE (0.42) | ACHEBCHECHRM4DRD2DRD4 | |
| SCHEMBL7303537 | 0.91 | LTA4H (0.47) | ACHEBCHE | |
| SCHEMBL7309154 | 0.91 | ACHE (0.45) | ACHEBCHECHRM4 | |
| SCHEMBL7310167 | 0.91 | CACNA1G (0.42) | CACNA1G | |
| SCHEMBL7314334 | 0.91 | CACNA1G (0.42) | CHRM4CACNA1GDRD2DRD4 | |
| SCHEMBL7314139 | 0.91 | CACNA1G (0.42) | CACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |